Updated September 15, 2012 – Thursday night players removed from Week 2 rankings
D Rankings
| Rank | Team | Opponent |
| 1 | Houston Texans | at JAC |
| 2 | New York Giants | TB |
| 3 | San Francisco 49ers | DET |
| 4 | Baltimore Ravens | at PHI |
| 5 | Pittsburgh Steelers | NYJ |
| 6 | New York Jets | at PIT |
| 7 | New England Patriots | ARI |
| 8 | Cincinnati Bengals | CLE |
| 9 | Oakland Raiders | at MIA |
| 10 | Dallas Cowboys | at SEA |
| 11 | Denver Broncos | at ATL |
| 12 | Atlanta Falcons | DEN |
| 13 | Philadelphia Eagles | BAL |
| 14 | Buffalo Bills | KC |
| 15 | Kansas City Chiefs | at BUF |
| 16 | Cleveland Browns | at CIN |
| 17 | Seattle Seahawks | DAL |
| 18 | San Diego Chargers | TEN |
| 19 | Tennessee Titans | at SD |
| 20 | Indianapolis Colts | MIN |
| 21 | Miami Dolphins | OAK |
| 22 | Washington Redskins | at STL |
| 23 | Detroit Lions | at SF |
| 24 | New Orleans Saints | at CAR |
| 25 | Minnesota Vikings | at IND |
