Running Backs
| Rank | Player | Team | Opponent |
| 1 | DeMarco Murray | DAL | at NYG |
| 2 | Jamaal Charles | KC | at OAK |
| 3 | Matt Forte | CHI | vs TB |
| 4 | Marshawn Lynch | SEA | vs ARI |
| 5 | Eddie Lacy | GB | at MIN |
| 6 | Mark Ingram | NO | vs BAL |
| 7 | LeSean McCoy | PHI | vs TEN |
| 8 | Justin Forsett | BAL | at NO |
| 9 | Arian Foster | HOU | vs CIN |
| 10 | C.J. Anderson | DEN | vs MIA |
| 11 | Andre Ellington | ARI | at SEA |
| 12 | Denard Robinson | JAC | at IND |
| 13 | Rashad Jennings | NYG | vs DAL |
| 14 | Trent Richardson | IND | vs JAC |
| 15 | Isaiah Crowell | CLE | at ATL |
| 16 | Ryan Mathews | SD | vs STL |
| 17 | Frank Gore | SF | vs WAS |
| 18 | Tre Mason | STL | at SD |
| 19 | Alfred Morris | WAS | at SF |
| 20 | Jeremy Hill | CIN | at HOU |
| 21 | Lamar Miller | MIA | at DEN |
| 22 | Jonas Gray | NE | vs DET |
| 23 | Joique Bell | DET | at NE |
| 24 | Steven Jackson | ATL | vs CLE |
| 25 | Giovani Bernard | CIN | at HOU |
| 26 | Charles Sims | TB | at CHI |
| 27 | Jerick McKinnon | MIN | vs GB |
| 28 | Shane Vereen | NE | vs DET |
| 29 | Bishop Sankey | TEN | at PHI |
| 30 | Terrance West | CLE | at ATL |
| 31 | Alfred Blue | HOU | vs CIN |
| 32 | Fred Jackson | BUF | vs NYJ |
| 33 | Reggie Bush | DET | at NE |
| 34 | Bryce Brown | BUF | vs NYJ |
| 35 | Christopher Ivory | NYJ | at BUF |
| 36 | Chris Johnson | NYJ | at BUF |
| 37 | Dan Herron | IND | vs JAC |
| 38 | Darren Sproles | PHI | vs TEN |
| 39 | Ben Tate | MIN | vs GB |
| 40 | Branden Oliver | SD | vs STL |
