Running Back
| Rank | Player | Team | Opponent |
| 1 | LeSean McCoy | PHI | vs. JAC |
| 2 | Matt Forte | CHI | vs. BUF |
| 3 | Jamaal Charles | KC | vs. TEN |
| 4 | Marshawn Lynch | SEA | vs. GB |
| 5 | Adrian Peterson | MIN | at STL |
| 6 | Eddie Lacy | GB | at SEA |
| 7 | DeMarco Murray | DAL | vs. SF |
| 8 | Montee Ball | DEN | vs. IND |
| 9 | Le’Veon Bell | PIT | vs. CLE |
| 10 | Andre Ellington | ARI | vs. SD |
| 11 | Alfred Morris | WAS | at HOU |
| 12 | Doug Martin | TB | vs. CAR |
| 13 | Arian Foster | HOU | vs. WAS |
| 14 | Zac Stacy | STL | vs. MIN |
| 15 | Giovani Bernard | CIN | at BAL |
| 16 | C.J. Spiller | BUF | at CHI |
| 17 | Rashad Jennings | NYG | at DET |
| 18 | Frank Gore | SF | at DAL |
| 19 | Toby Gerhart | JAC | at PHI |
| 20 | Reggie Bush | DET | vs. NYG |
| 21 | Ryan Mathews | SD | at ARI |
| 22 | Maurice Jones-Drew | OAK | at NYJ |
| 23 | Ben Tate | CLE | at PIT |
| 24 | Bernard Pierce | BAL | vs. CIN |
| 25 | Shane Vereen | NE | at MIA |
| 26 | Joique Bell | DET | vs. NYG |
| 27 | Chris Johnson | NYJ | vs. OAK |
| 28 | Fred Jackson | BUF | at CHI |
| 29 | Steven Jackson | ATL | vs. NO |
| 30 | Lamar Miller | MIA | vs. NE |
| 31 | Pierre Thomas | NO | at ATL |
| 32 | Shonn Greene | TEN | at KC |
| 33 | Trent Richardson | IND | at DEN |
| 34 | Knowshon Moreno | MIA | vs. NE |
| 35 | Christopher Ivory | NYJ | vs. OAK |
| 36 | Stevan Ridley | NE | at MIA |
| 37 | Bishop Sankey | TEN | at KC |
| 38 | Mark Ingram | NO | at ATL |
| 39 | LeGarrette Blount | PIT | vs. CLE |
| 40 | Danny Woodhead | SD | at ARI |
